Peptide Active Data Details
Basic Peptide Information
DICL ID
DICL_Pep_06953
Ion Channel
Piezo1
Peptide Function
Inhibitor
Gene Name
Piezo1
Activity Data (nM)
IC50
Not available
Ki
Not available
EC50
1000 nM
Kd
Not available
Biologically Active
Not specified
Sequence Information
Peptide Sequence
GCLEFWWKCNPNDDKCCRPKLKCSKLFKLCNFSF
Peptide UniProt Accession
UniParc
UPI00003CEC11
Peptide Synonyms/Alias
[GsMTx4; 1209500-46-8; GsMTx-4; H-Gly-DL-Cys(1)-DL-Leu-DL-Glu-DL-Phe-DL-Trp-DL-Trp-DL-Lys-DL-Cys(2)-DL-Asn-DL-Pro-DL-Asn-DL-Asp-DL-Asp-DL-Lys-DL-Cys(3)-DL-Cys(1)-DL-Arg-DL-Pro-DL-Lys-DL-Leu-DL-Lys-DL-Cys(2)-DL-Ser-DL-Lys-DL-Leu-DL-Phe-DL-Lys-DL-Leu-DL-Cys(3)-DL-Asn-DL-Phe-DL-Ser-DL-Phe-NH2; CHEBI:194078; HB1161; AKOS024458413; C185H273N49O45S6; CID:90488987]
Peptide Species
Grammostola rosea (Chilean rose tarantula) (Grammostola spatulata)
Peptide Name
M-theraphotoxin-Gr1a
CAS Number
1209500-46-8
Experimental Conditions
pH
Not mention
Holding Potential (mV)
Not mention
Temperature
Not mention
Test Method
Patch-clamping
Test Species
Not specified
Binding Information
Binding Site
Extracellular domain
Binding Site Residue
Not specified
Ion Channel Information
Gene Abbreviation (ABB)
Piezo
Ion Channel UniProt Accession
Source Organism
Rattus norvegicus (Rat)
References & Disease Information
Disease
Not specified
PubChem CID
URL
Not available
PMID
Patent
Not available